Alan C Sartorelli Selected Research

n-butyl nitrite (butyl nitrite)

1/2005

Synthesis and biological evaluation of 2',3'-didehydro-2',3'-dideoxy-9-deazaguanosine, a monophosphate prodrug and two analogues, 2',3'-dideoxy-9-deazaguanosine and 2',3'-didehydro-2',3'-dideoxy-9-deazainosine.

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Alan C Sartorelli Research Topics

Disease

30	Neoplasms (Cancer) 03/2016 - 01/2005
10	Carcinoma (Carcinomatosis) 01/2016 - 01/2002
10	Hypoxia (Hypoxemia) 02/2013 - 02/2003
9	Leukemia 01/2016 - 04/2003
8	Colorectal Neoplasms (Colorectal Cancer) 03/2014 - 01/2004
6	Ovarian Epithelial Carcinoma 03/2016 - 02/2006
6	Colonic Neoplasms (Colon Cancer) 12/2011 - 01/2004
3	Ovarian Neoplasms (Ovarian Cancer) 03/2014 - 02/2006
3	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/2008 - 11/2004
2	Fanconi Anemia (Fanconi's Anemia) 01/2016 - 03/2012
2	Neuroblastoma 08/2011 - 08/2009
2	Glioma (Gliomas) 05/2011 - 11/2008
2	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 01/2008 - 01/2002
1	Adenocarcinoma 01/2016
1	Wounds and Injuries (Trauma) 08/2011
1	Ataxia Telangiectasia (Louis Bar Syndrome) 09/2007
1	Tuberculosis (Tuberculoses) 01/2007
1	Melanoma (Melanoma, Malignant) 01/2005
1	Leukemia L1210 01/2005
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2005

Drug/Important Bio-Agent (IBA)

12	ProdrugsIBA 05/2015 - 01/2005
11	laromustine (VNP40101M)IBA 06/2013 - 01/2005
10	DNA (Deoxyribonucleic Acid)IBA 01/2016 - 06/2004
10	O(6)-Methylguanine-DNA MethyltransferaseIBA 05/2015 - 12/2008
8	Proteins (Proteins, Gene)FDA Link 05/2015 - 04/2004
6	Cisplatin (Platino)FDA LinkGeneric 03/2016 - 06/2004
6	Oxygen (Dioxygen)IBA 08/2012 - 11/2008
6	hydrazine (hydrazine dihydrochloride)IBA 11/2011 - 01/2005
6	Butyrates (Butyrate)IBA 05/2008 - 01/2002
5	Carmustine (FIVB)FDA Link 08/2014 - 05/2005
5	GuanineIBA 06/2013 - 12/2008
5	1,2- bis(methylsulfonyl)- 1- - (2- chloroethyl)- 2- ((1- (4- nitrophenyl)ethoxy)carbonyl)hydrazineIBA 09/2012 - 06/2005
4	3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine)IBA 03/2016 - 02/2006
4	Carboplatin (JM8)FDA LinkGeneric 03/2016 - 02/2006
4	Antineoplastic Agents (Antineoplastics)IBA 01/2016 - 02/2013
4	Temozolomide (Temodar)FDA LinkGeneric 06/2013 - 12/2008
4	Pharmaceutical PreparationsIBA 10/2012 - 02/2003
4	Cytotoxins (Cytolysins)IBA 09/2012 - 01/2005
4	EnzymesIBA 11/2011 - 02/2003
3	Doxorubicin (Adriamycin)FDA LinkGeneric 03/2016 - 06/2004
3	PlatinumIBA 03/2016 - 01/2016
3	olaparibIBA 03/2016 - 09/2012
3	Alkylating AgentsIBA 06/2013 - 11/2010
3	O(6)-benzylguanineIBA 02/2013 - 11/2011
3	Alkyl and Aryl TransferasesIBA 02/2013 - 04/2006
3	Tretinoin (Retinoic Acid)FDA LinkGeneric 09/2009 - 04/2004
3	Dietary Fiber FDA Link 05/2008 - 07/2004
3	Calcibiotic Root Canal SealerIBA 01/2008 - 01/2004
3	Butyric Acid (Butanoic Acid)IBA 01/2006 - 01/2002
3	Lithium ChlorideIBA 11/2004 - 04/2003
2	Etoposide (VP 16)FDA LinkGeneric 03/2016 - 08/2009
2	Paclitaxel (Taxol)FDA LinkGeneric 01/2016 - 02/2006
2	Mitomycin (Mitomycin-C)FDA LinkGeneric 01/2016 - 01/2005
2	MethyltransferasesIBA 03/2014 - 06/2013
2	Poly(ADP-ribose) Polymerase InhibitorsIBA 03/2014 - 09/2012
2	Oxidoreductases (Dehydrogenase)IBA 11/2011 - 05/2011
2	reversanIBA 08/2011 - 08/2009
2	beta CateninIBA 01/2008 - 01/2002
2	Phosphotransferases (Kinase)IBA 09/2007 - 01/2007
2	Ribonucleotide Reductases (Ribonucleotide Reductase)IBA 09/2007 - 06/2004
2	Complementary DNA (cDNA)IBA 01/2006 - 09/2004
2	Transcription Factors (Transcription Factor)IBA 11/2004 - 04/2004
1	RNA (Ribonucleic Acid)IBA 01/2016
1	MK 2206IBA 01/2016
1	IsoenzymesIBA 08/2014
1	Topoisomerase InhibitorsIBA 03/2014
1	7-nitro-4-(phenylthio)benzofurazanIBA 10/2012
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 10/2012
1	Superoxides (Superoxide)IBA 10/2012
1	DNA alkyltransferaseIBA 08/2012
1	TransferasesIBA 03/2012
1	Biological ProductsIBA 08/2011
1	Small Interfering RNA (siRNA)IBA 08/2011
1	Adenosine Triphosphate (ATP)IBA 08/2011
1	multidrug resistance-associated protein 1IBA 08/2009
1	Vincristine (Oncovin)FDA LinkGeneric 08/2009
1	SolutionsIBA 05/2008
1	Diazepam (Valium)FDA LinkGeneric 01/2008
1	trichostatin A (A 300)IBA 01/2008
1	hexamethylene bisacetamide (HMBA)IBA 01/2008
1	phorbolIBA 01/2008
1	theasinensin AIBA 01/2008
1	Histone Deacetylases (Histone Deacetylase)IBA 01/2008
1	Thioguanine (Tioguanine)FDA Link 01/2008
1	HypoxanthineIBA 01/2008
1	Histone Deacetylase InhibitorsIBA 01/2008
1	Mitochondrial DNA (mtDNA)IBA 09/2007
1	2- morpholin- 4- yl- 6- thianthren- 1- yl- pyran- 4- oneIBA 09/2007
1	beta-apocarotenoid-14',13'-dioxygenase (ADO)IBA 01/2007
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 01/2006
1	1,2- bis(methylsulfonyl)- 1- (2- chloroethyl)hydrazineIBA 06/2005
1	Sulfhydryl Compounds (Thiols)IBA 06/2005
1	methyl isocyanateIBA 01/2005
1	1-methylimidazoleIBA 01/2005
1	PorfiromycinIBA 01/2005
1	Hemoglobins (Hemoglobin)IBA 01/2005

Therapy/Procedure

4	Drug Therapy (Chemotherapy) 01/2016 - 08/2009
4	Therapeutics 09/2012 - 02/2006
2	Radiotherapy 03/2012 - 01/2005
1	Aftercare (After-Treatment) 03/2014